B

B10 virus 578t B119L polyprotein 12-13 B602L protein 12-13

Baboon cytomegalovirus (BaCMV) 268t, 271/ Bacillus subtilis, associated phages 554, 557 Bacterial viruses see Bacteriophage(s) Bacteriophage(s)

double stranded DNA see Double stranded DNA

(dsDNA) bacteriophages double stranded RNA see Double stranded RNA

(dsRNA) bacteriophages dsDNA see Double stranded DNA (dsDNA)

bacteriophages dsRNA see Double stranded RNA (dsRNA)

bacteriophages evolution 571—576 capsid proteins 575 co-infections 572 evolutionary connections 575 genome comparisons 573 genome organization 572 host cell co-evolution 575 mechanisms 572, 573 filamentous ssDNA see Filamentous ssDNA

bacteriophages historical aspects 537

icosahedral dsDNA see Icosahedral dsDNA

bacteriophages icosahedral ssDNA see Icosahedral ssDNA

bacteriophages library 505 lysogeny 567 in molecular biology 538 nonhomologous recombination 572-573, 573-575, 574/ genome comparisons 573 horizontal transfer 573 novel gene acquisition 575 novel sequence joints 573 populations 572 productive infections 572 replication 553—560

single-stranded RNA see Single-stranded RNA

bacteriophages ssRNA see Single-stranded RNA bacteriophages T4-even phages 555

T4-like phages see T4-like bacteriophages T7-like phages see T7-like bacteriophages tailed see Caudovirus(es); Tailed bacteriophages transcription regulation 560—571 AsiA 563 elongation 561

host RNAP-mediated elongation 560 initiation 561 isomerization 561

promoter binding 561 RNAP structure 560 Bacteriophage Bam35 genome 521 host range 519-520 Bacteriophage Bxbl 570 Bacteriophage Cp-1 557 Bacteriophage j29 evolution 575 genome size 552 replication 556-557

DNA polymerase 557-558, 557/ membrane-localized proteins 558 replication forks 557/, 558 sliding back mechanism 557-558 Bacteriophage fd 508-509 composition 507 genome packaging 507, 508/ pIII 509 pVIII

central region 508-509 composition 507, 508, 508/ N-terminal region 508 pentapeptide motifs 508t, 509 structure 507, 507t Bacteriophage Ff assembly pathway 505 DNA synthesis 510

host-encoded polymerases 510 pII 510 genome 507/ genome packaging 505 infection 508-509 F pilus 509-510 Tol-Pal system 509-510, 510/ post-transcriptional modification 510-511 protein synthesis 510

host-encoded polymerases 510 pIII maturation 511 pIV 511 pVIII 511 transcription 510-511 translation 511 virus assembly 511

pIV channel conformations 511 progeny elongation 511-512 pV-coated genome 511 sites 511 Bacteriophage HK022 570 Bacteriophage HK97 coat protein folding evolution 575 evolution 573, 574/ phylogeny 552-553 Bacteriophage j6 523

structure 524/ Bacteriophage L5 570 Bacteriophage l

CII accumulation 568 genome 554 life cycle 567/ lysis 567

lysogeny 567, 567/; 568 lytic growth 569 persistence 570 suppression mechanisms 570 terminator role 570 transcription regulation 569-570 promoters 568, 568/ PaQ 568 PInt 568 PL 568, 569 PR 554, 568 Pre 568 prophage excision 568/ 569 Fis protein 569 Int protein 569 Xis protein 569 regulatory strategies 567 replication 554 host proteins 554

protein O 554 site-specific prophage insertion 567-568 structure 547, 547f, 548-549 Bacteriophage M13

cloning vector function 512 genome 506, 507f gene expression 506 intergenic region 506 phage display 512 Bacteriophage Mu genome 558 replication 558 DnaB 558 protein PriA 558 transposome formation 558 Bacteriophage N4 566 regulatory strategies 566 transcription early genes 566 late genes 566-567 middle genes 566 promoters 566 RNAPII 566 vRNAP 566 Bacteriophage P2 570 Bacteriophage P22

evolution 575 Bacteriophage jX174 DNA packaging 535 DNA replication 532, 533f evolution 536 genetic map 531f history 529-530 host cell attachment 532 host cell penetration 532 morphogenesis 535 nomenclature 529-530 replication 558 GpC protein 559 preprimosome assembly

558-559 protein A 559 SSB protein 558-559 stage I 558-559 stage II 559 stage III 559 structure 530f procapsid 534f Bacteriophage PRD1 genome 521

encoded proteins 518t organization 521, 521f host range 519-520 inverted terminal repeats 557 life cycle 519-520 DNA entry 520 host cell lysis 521 receptor recognition 520 replication initiation 520, 557-558 structure 518, 519f membrane 518t, 519 vertices 520f

X-ray crystallography 519f Bacteriophage SPP1 genome 554 replication 554

associated host proteins 554 helicase 554 primase 554 Bacteriophage T3 563 coupled transcription 564 DNA entry 564 early transcription 564 promoters 564-565 termination 564-565 late transcription 564/, 565 class III genes 565 termination 565 middle transcription 565 class II genes 565

promoters 564/, 565 regulatory strategies 563 coupled transcription 564 DNA entry 564 early transcription 564 late transcription 565 middle transcription 565 temporal gene expression 564 transcription regulation 565 temporal gene expression 564 early genes 564 early gene transcription 564 transcription regulation 565 Bacteriophage T4 547, 547/, 561 DNA injection 550 early transcription Alt protein 562 early promoters 562 a70 5 62 genome map 562/ genome size 552 late transcription 563 gp33 563 gp45 563 gp55 563 middle transcription 562 ADP-ribosylation 562-563 promoters 563 RNA synthesis 562/, 563 protein injection 550 regulatory strategies 561 early transcription 562 late transcription 563 middle transcription 562 replication 555/ replication forks 555 structure 548, 549/ tails/tail fibers 549 Bacteriophage T5 550 Bacteriophage T7 563 coupled transcription 564 DNA entry 564 early transcription 564 promoters 564-565 termination 564-565 genetic map 564/ late transcription 564/, 565 class III genes 565 termination 565 middle transcription 565 class II genes 565 promoters 564/, 565 open reading frames 563-564 regulatory strategies 563 coupled transcription 564 DNA entry 564 early transcription 564 late transcription 565 middle transcription 565 RNA polymerase 565 RNA processing 566 temporal gene expression 564 transcription regulation 565 RNA polymerase 565 RNA processing 566 temporal gene expression 564 early gene transcription 564 transcription regulation 565 class II genes 565-566 late genes 565-566 RNAP phosphorylation 566 T7 DNA host cell entry 565-566 Baculoviridae 477 Baculovirus(es)

occlusion bodies 279-280, 479-480

function 280 spindle production 280 virion structure 279-280 Bahia Grand Group, animal rhabdoviruses 28 Bahia Grand virus (BGV) 28 BALB/c mice, MHV-68 pathogenesis 318

Bam35 bacteriophage see Bacteriophage Bam35 Barfin flounder nervous necrosis virus (BFNNV) 460 Barnard, J E, Ectromelia virus 308 Barur virus (bARV) 28 Basal cell(s)

HPV see Human papillomavirus(es) (HPVs) papillomavirus life cycle 164 Bat(s)

paramyxovirus host 175—177, 180—181 BBMV see Broad bean mottle virus (BBMV) B cell(s)

transformation, lymphocryptovirus 337 see also Antibodies BEFV see Bovine ephemeral fever virus (BEFV) BEL, LTR retrotransposons 200 p-amyloid plaque visualization, bacteriophage display 512 Betaentomopoxvirus 279

characteristics 280t Betaherpesvirinae 257, 267, 268t Betaherpesvirus(es)

associated genera 267, 268t genome alphaherpesviruses vs. 268-269 gammaherpesviruses vs. 268-269 sequences 267 Betanodavirus(es) infection fish 459-460 type species 459-460 Betaretrovirus 148, 301, 368 Betaretrovirus(es) genome 368, 369/ ruminants 148—155 Bet gene/protein see Foamy viruses BHV1 see Bovine herpesvirus 1 (BHV1) BHV2 see Bovine herpesvirus 2 (BHV2) Biotechnology bacteriophages, filamentous ssDNA 512 Biotype(s)

bovine viral diarrhea viruses 79 definition 77 Birnaviridae 462 Birnavirus(es)

fish see Fish birnavirus(es) genera 462 shellfish 476 Bison, bovine herpesvirus 2 70 Bivalves, definition 470 BIVR29 infections (cattle) experimental infection 55 serology 53 'Black spot' 91-92 Blood-brain barrier SIV infection 364 Blood transfusions vCJD risk 76 Bluetongue virus(es) (BTV) 43-50 capsid assembly 48 VP3 48 VP7 48 capsid structure outer capsid proteins 44 cell egress 48

calpactin light chain 48 NS3/NS3A proteins 48 Tsg101 48 core particle 44, 45/

trimeric proteins 44 epidemiology 49 genome 45, 46t noncoding regions 46 sequence conservation 46 terminal sequences 46 history 43

host cell attachment 46 VP2 46 VP5 46-47 host cell entry 46 infection clinical features 48

control 49 immunity 49 pathogenesis 48 prevention 49 sheep 48 morphology 43-44, 44/ protein synthesis 47 NS1 47 NS2 47

phosphorylation 47 replication 46 structure 44, 44/ transcription 47 VP4 47 VP6 47 transmission 48, 49 vaccines/vaccination 49 inactivated 49 live attenuated 49 virion properties 43 BMV see Brome mosaic virus (BMV) Bohle iridovirus (BIV), host range 296 Bone marrow

Visna-Maedi virus infection 249 Bovine enterovirus(es) (BEV) 103 classification 103 genome 106

virion structure 108, 108/ Bovine enzootic fever see Bovine ephemeral fever virus (BEFV) Bovine ephemeral fever virus (BEFV) antigenic variation 63 site G1 63-64 site G2 63-64 site G3 63-64 site G4 63-64 epizootiology 58

vectors 58 genome 60, 61/ geographical distribution 58 history 57-58 infection immune response 64 pathogenesis 59 pathology 59 taxonomy 58, 59/ transcription 62

a coding region 62-63 P coding region 62-63 g coding region 62-63 polyadenylation signal 62-63 transmission 27 vaccines/vaccination 64, 65 virion morphogenesis 59 virion structure 59, 60/ G protein 59-60 nucleocapsid 59-60 virus encoded proteins 60 GNS protein 62 G protein 61, 64/ L protein 62 M protein 61 N protein 60 P protein 61

small nonstructural proteins 62 Bovine gammaherpesvirus(es) distribution 68 history 66 transmission 68 Bovine herpesvirus(es) 65—71, 67t antigenic relationships 68 classification 66, 67t epidemiology 68 geographical distribution 68 history 65 infection clinical disease 69 control 70

immune response 70 latency 68 pathogenesis 68

Bovine herpesvirus(es) (continued) prevention 70 replication 66 structure 66 Bovine herpesvirus 1 (BHV1) 67t genital disease control 70 history 65-66 latency 68

vaccines/vaccination 70 Bovine herpesvirus 2 (BHV2) 67t history 66 mammilitis 69 Bovine herpesvirus 3 (BHV3) 66 Bovine herpesvirus 4 (BHV4) 66, 67t Bovine herpesvirus 5 (BHV5) 67t Bovine herpesvirus 6 (BHV6) 67t Bovine immunodeficiency virus(es) (BIV) 50—57 classification 50 clinical features 54 economic impact 56 epidemiology 54 evolution 53 genetics 53

variability 53 genome 52

open reading frames 52-53 geographical distribution 51, 51/

prevalence 51 history 50 host range 53 infection clinical features 54 control 56 histopathology 55 immune response 55 pathology 55 prevention 56 secondary diseases 55 propagation 53

associated cell types 53 serology 53

BIVR29-infected cattle 53 taxonomy 50 tissue tropism 54 transmission 54 iatrogenic 54 PCR detection 54 variability 53 virion structure 52, 52/ viral core 52 viral enzymes 52 Bovine influenza see Bovine ephemeral fever virus (BEFV)

Bovine malignant catarrhal fever (MCF) causative agents 66, 68, 69-70 clinical features 69-70 control 70 history 66 hosts 66, 68 pathogenesis 68 prevention 70 Bovine papillomavirus 1 (BPV-1) 167 genome 166/ pathology 165 research history 161-162 structure 167/

viral protein functions 166-167 E2 171 E4 167 E6 166-167 E7 166-167 L1 167 L2 167

Bovine papillomavirus 4 (BPV-4) 168 Bovine papular stomatitis virus (BPSV) 182

host range 183 Bovine respiratory syncytial virus genome 177, 178/ reverse genetics 179-180 Bovine spongiform encephalopathy (BSE) 71—77 associated cases 71, 72

epidemiology 72, 73/

mathematical models 72 geographical distribution 73, 74/ history 71

incubation period 71—72 novel forms 73—74 origin 71 prevention active testing 72, 73 legislation 71

passive surveillance 72, 73 specified bovine offal ban 72 tissue distribution 71—72 transmission 72—73 Bovine viral diarrhea virus(es) 77—84 characteristics 81

virion inactivation 81 virion structure 81 history 78 biotypes 79 early reports 78 genotypes 80 isolation 79

modified live virus release 79 postvaccinal mucosal disease 79 reduction and eradication programs 81 infection see below molecular biology 82 genome 80/, 81, 82 viral proteins 82 viral replication 83 Bovine viral diarrhea virus 1 (BVDV-1)

type 2 vs. 81, 82 Bovine viral diarrhea virus 2 (BVDV-2)

type 1 vs. 81, 82 Bovine viral diarrhea virus infection clinical features 78, 78/ cytopathic type 78/, 79 noncytopathic type 78/, 81 control 83 detection 83

hemorrhagic syndrome 80—81 BVDV1 vs. BVDV2 82 clinical symptoms 80—81 mucosal disease disease characteristics 78—79 etiology 79 persistent 79 BPSV see Bovine papular stomatitis virus (BPSV) BPV-1 see Bovine papillomavirus 1 (BPV-1) Brain pseudorabies virus infection 196 see also Central nervous system (CNS) Breast cancer mouse mammary tumor virus model 322—323

Simian retrovirus D 368—369, 373 Bridge vector(s) 375

vector transmission, animal viruses 231 Bronchopneumonia, morbillivirus infection 227 Brown trout reovirus 430t

BSE see Bovine spongiform encephalopathy (BSE)

Bubaline herpesvirus 1 (BuHV1) 67t

Budding avian hepadnavirus 409/, 411 duck hepatitis B virus 409/, 411 equine infectious anemia virus 112 foamy virus 129 vesicular stomatitis virus 240 Buffalo, capripoxvirus infection 84—85 Bunyaviridae 213 Burkitt's lymphoma

Simian retrovirus D 373 Burnett, F M, Ectromelia virus 308 Burst size definition 576 haloviruses 577

methanogenic Archaea-infecting viruses 577 Bushpig (Potamochoerus porcus), African swine fever virus 9 Bxbl bacteriophage 570

How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book


Post a comment