P

p53 212-213, 253-257 partially p-conjugated oligomer 16 poly(ethylene oxide) (PEO) 80 peptidases 210, 231

«-peptides 20, 36, 39, 41, 43, 45, 46, 51, 53, 58-59, 61-62, 65, 117-118, 181, 184-185, 212, 215-216, 229-231, 236-237, 239, 241243, 247, 253-255 «,b-peptide 57, 62-64 «,g-peptide 65 b,g-peptide 57, 61-62 b-peptide 20, 22, 37, 39-40, 43-48, 50, 53, 55-56, 58-60, 65-68, 134-136, 175, 178182, 184-188, 190, 210, 212-213, 215-217,

230, 231, 236, 239-243, 245-247, 253-255 g-peptide 37-39, 41-44, 47-48, 56, 59, 60,

65-66, 215-216 d-peptide 41, 56-57 d,l-peptide 52-53 o-peptide hybrids 63, 65 peptide amphiphile 137-138 peptide nucleic acid (PNA) 134, 210, 230231, 237, 251, 253, 304 peptidomimetic 17, 66, 210, 212, 215, 224,

231, 248

peptoid 20-22, 173, 178, 180-181, 184, 210, 214-215, 230-231, 237-238, 240-241, 244-245, 255-256 persistence length 294, 341, 343, 347, 373, 384

perylene 86-87, 395-397

phage display 270-272, 274, 276 phage-enzyme 271 phenotype 251, 268-269, 276 phenylene ethynylene 92, 97, 201, 203, 207,

209, 235, 244, 350, 418, 419, 420 phosphorothiate 304 photoluminescence 209 a-pinene 201-202 piperazine 5, 203

p-p interaction 9, 11, 18-19, 28, 35, 66, 8587, 89, 92-93, 96, 101, 111, 116-117, 130132, 137, 163, 200-202, 207, 294-295, 312, 387, 396, 403, 417, 419 poly(2,3-quinoxaline) 337 poly(acrylate) 220

poly(dialkoxy-1,4-phenylene-olt-2,5-furan) 24

poly(phenylacetylene) 343-345, 351-353,

358, 360-362, 412 poly(phenylisocyanide) 372 poly(triarylmethyl methacrylate) 333-334 polyacetylene 23, 338, 342-343, 349, 357358, 360, 367, 389 polyamide 20, 111, 210, 220-221, 223, 249 polyaniline 350 polydispersity 222, 370, 384 polyelectrolyte 347, 353, 354, 389 polyethylene glycol chain 202 polyguanidine 23-24, 332, 337-338, 350 polyhydroxybutanoate 182 polyisocyanate 23-24, 338-343, 349, 355356, 360, 367, 377 polyisocyanide 23-24, 222, 332, 336-337, 367-377, 380-385, 387-389, 391-392, 394-396, 398 polyisocyanopeptide 373, 383, 394-395 polymeric aggregate 136 polymethacrylamide 24 polymethacrylate 23-24, 334, 359-360 polymorph 52, 218, 220-221, 294 poly-N-methylated peptide 22 polypeptide 20-21, 35-37, 52, 60, 67, 147, 150-151, 155, 164-165, 173-174, 178, 185186, 190, 267, 270-271, 276, 278, 280, 286, 355, 417

polyproline 20-23, 148, 214, 231, 241, 255 polypyrrolinone 17 polysilane 338, 341-342, 350, 356, 368 polythiophene 25, 350, 397 pore 52, 116-118, 120 porphyrin 207-208, 302, 394 preorganization 13, 40, 408 proline 20, 41, 47-48, 59, 140, 148-149, 152-154, 156, 279, 415-416

protease 210, 231, 238, 276, 280 proteasome 213

protein design 150, 154, 166, 267-268, 278, 286

proteolysis 280-281 pyrene 122-123

197, 206-207, 209, 391, 411 pyrrole 66, 121-122, 209, 232-233 quadruple helix 127

q quadruple hydrogen bonding motif 126 quaternary structure 84, 277, 298, 405

r racemization 4, 24, 334-335, 355 radical polymerization 334 Ramachandran 5, 21-22, 52, 147-148, 150151, 156

random coil 25, 109, 201, 214, 331, 350, 372-373, 380, 410, 413, 417-418, 420-421

receptor 12, 76, 195-199, 201-204, 206207, 209, 215-216, 224-225, 236, 239-240, 245-246, 252, 272-273, 283, 297-298, 301, 308, 312-313, 315, 321, 347 recognition 25, 58, 77-78, 95, 103, 116, 132, 195-196, 204, 207, 210, 212-213, 216-219, 238, 240, 252, 272, 274-275, 285, 291, 299, 302, 307, 320-321, 333-334, 347, 359-360, 404, 408-409, 423 remote intrastrand interaction 35-36, 44, 61, 67-68

replication 116, 140-141, 249, 292, 297, 354, 389

repulsive interaction 3, 7, 23, 119, 124, 125, 371, 408

resolution 148-149, 309, 333, 336, 357, 360, 423

197, 222, 332 rhombohedral 218, 220, 223 ribbon 4, 5, 13, 17, 47, 79-80, 152, 166, 301,

415, 417, 419-420 ribose 205, 232, 270 ribosome display 275, 280 ribozymes 293, 297-298, 300, 301-303, 307, 313, 319

294, 341, 346, 373, 381, 383, 387 rod 4-5, 24, 79, 95, 137-138, 223, 297, 315,

salt bridge 36, 43-44, 127, 129, 175, 180, 213, 230

scanning tunneling microscopy (STM) 135136, 418, 420-422 secondary structure 20, 22, 28, 35-36, 39, 47, 50-52, 54, 59, 63-68, 82, 103, 109, 113, 134, 137, 147-148, 150, 163-164, 167, 213216, 229-230, 269, 272, 277-281, 291, 294, 302, 367, 404-406, 409-411, 413-416, 421 sedimentation equilibrium experiment 217, 280

selection 268-277, 280, 284-286, 291, 303,

305-307, 409 systematic evolution of ligands by exponential enrichment (SELEX) 299, 306-307 self-assembled monolayer (SAM) 220, 409, 417

self-assembly 84, 112, 121, 136-137, 139, 291-292, 311-312, 315-317, 353, 403, 411, 414, 416, 419-422 self-association 99-100, 122, 165 self-replication 140-141 sensing 25, 103, 301, 321, 331, 338, 345,

347, 358, 367 sergeants and soldiers 339-340, 342-345 b-sheet 17, 51-52, 65, 109, 148, 158, 162, 164, 165, 167, 210, 224, 247, 367, 382, 406, 412-418, 420-421 b-sheet monolayer 224 sheet structure 36, 58, 162, 165, 167, 413, 415-420

side chain 10, 17, 22, 24, 36-39, 43-45, 47, 50-51, 55, 79-80, 86, 93, 96, 103, 113-114, 117, 137, 149, 162-163, 165, 167, 173, 175-176, 179-180, 182-184, 188, 211-214, 222-224, 230-231, 239, 241-242, 244, 246, 253-256, 284, 294, 356, 368, 372, 380-384, 387, 389, 391, 413, 417, 419 silica 123, 224, 359, 412 simulation 44-45, 48, 55, 59, 82, 173-175, 178-180, 182, 184, 186-187, 190, 247, 423 siRNAs 293, 315, 319 solid-liquid interface 405, 418, 421 solvent effect 75-76, 180 solvophobic effect 3, 8, 18, 35, 75, 77-78,

81, 84, 200 solvophobic interaction 77-80, 83, 85, 88,

91, 93, 101, 132, 403 somatostatin 215-216, 236, 239-240 specific rotation 337, 374-375 stability constant 199, 201, 203, 205

stacking 9, 18, 86, 89, 111, 116-117, 130132, 137, 312, 396 staphylococcal protein A 272-273 stereoregular 342, 345, 360, 374-375 stereoselectivity 381 steric effect 18, 23-24, 27, 99, 110 stop codon suppression 282-283 structure inducing codon 11 supramolecular chemistry 76-77, 96, 109,

116, 125, 315, 331-332, 363 supramolecular polymer 136-138 surface 75-78, 80-81, 95-96, 99-100, 103, 114, 118, 131, 195, 210, 212, 214-215, 217, 219, 223, 225, 229-230, 236-237, 242, 269, 272, 274, 276, 301, 320, 357, 389, 406-409, 412-415, 417, 420-423 surface pressure-area isotherm 410-411, 419, 421

switching 222, 298-299, 301-303, 308, 319, 338, 358

syn-pentane interaction 41-42, 59 t tailbiter 66-67

tautomer 122, 125-126

tectoRNA 300, 308, 310-313, 315, 318, 321

tectosquares 308, 314-315, 317, 321

teleinduction 381

template 13, 15-16, 45, 51, 127, 139-141, 152-154, 157, 163, 210, 220, 222, 252, 270, 277, 303, 305, 316-317, 320-321, 354, 382, 385-387 tensegrity 309 terephthalamide 236, 257 terphenyl 129, 235-236, 256-257 tertiary aliphatic amide 20, 22 tertiary structure 28, 68, 165, 167, 284, 291,

295, 405 tetrathiafulvalene 390 temperature gradient gel electrophoresis

(TGGE) 312 thermodynamic control 362, 377, 379, 406 thermogravimetric analysis 323 thiophene 25, 350, 395-396 Thorpe-Ingold effect 36 a-threofuranosyl nucleic acid (TNA) 304 torsion angle 5, 21-23, 36, 38-39, 59-60,

62, 64, 147, 153, 158 trans-1,2-diaminocyclohexane 25 trans-2-aminocycloalkyl carboxylic acid 4344

trans-2-aminocyclohexyl carboxylic acid (trans-ACHC) 39-40, 47, 62, 242

trans-2-aminocyclopentyl carboxylic acid

(trans-ACPC) 40, 43, 62 transcription 21, 112-113, 140, 237, 244,

249-253, 301, 305-306 transition temperature 356 transmission electron microscopy (TEM)

224, 312-313 transoid conformation 5, 11, 119, 207, 419 b,a,a-triad repeat 64 b,b,a-triad repeat 64 triose phosphate isomerase 270 triple helices 109, 112, 127-128, 297-298, 310

trispyridylamide 211-212 tube 80, 120

turn 17, 36, 45, 54-55, 58-61, 65, 147, 153, 155-160, 215-216, 239-240, 275, 279, 421-422 g-turn 45

turn mimic 421-422 b-turn mimetic 61, 215 twist sense 11, 13, 20, 22, 24, 40, 54, 56, 93, 130, 222, 255, 331-338, 340-341, 343-348, 350-353, 355-357, 359-363, 374, 377, 379-380, 384-385, 394 two-state transition 81-82, 103 tyrosine 200

van der Waals interaction 75, 77-78, 81-83,

88, 91, 103-104, 403 vancomycin 125 vaterite 220-221 vinyl polymer 24, 331, 333

w water 197

wire 5, 320-321, 389, 395, 398 Wurtzite 224

X-ray crystallography 4, 10, 14, 22, 49-50, 59, 60-62, 65, 85, 127, 130, 159, 164, 185, 197, 199, 210, 212, 274, 284-285, 297, 302, 310, 335-337 X-ray diffraction 39-40, 46, 50, 52, 64-66, 97, 126, 156-157, 167, 185, 357, 371, 383, 415

z zig-zag structure 130, 418 zipper 89, 99, 112-114, 130, 132, 139-140, 162

zwitterionic dimer 122, 128

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