Ooocx

phenylketonuria, 2:55-56 progeria, 1:1-3

psychiatric disorders, 3:214, 3:215 retinoblastomas, 4:153 sickle-cell disease, 2:137-138,

3:142 thalassemias, 2:140 thyroid hormone deficiency/resistance, 2:129-130 Y chromosomes, 4:176-177 In silico, defined, 2:212 In utero, defined, 2:81 In utero gene therapy, 2:81, 2:82 In vivo, defined, 2:212, 4:43 Initiation codons and sites. See Start codons (transcription) Initiation complexes, translation,

4:138 Initiation factors transcription, 4:107 translation, 4:138 INK family proteins, 1:107 Inquiries into the Human Faculty and Its Development (F. Galton), 2:17 Insect-resistant crops

Bacillus thuringiensis, 1:58, 1:64,

3:149, 4:134 ecological concerns, 1:68 genetically engineered, 1:63, 2:108 genomics role, 2:121 statistics, 1:57 transgenic plants, 2:106 Insects ants, chromosome numbers,

2:113 haplodiploidy, 2:113 holocentric chromosomes, 1:114 intracellular symbionts, 2:198 polytene chromosomes, 1:126,

1:136-137, 1:136 See also Fruit flies (Drosophila) Insemination donor, 4:24 intrauterine, 4:24 Insertion sequence (IS) elements, prokaryotes, 2:116, 2:117, 4:144-145 Insertional mutagenesis, 4:38 The Institute for Genomic Research

(TIGR), 2:173 Insulin as extranuclear hormone, 2:161 function, 1:209, 3:199 gene expression role, 2:66-67 genetically engineered, 1:63, 1:66, 1:72, 1:153-154, 2:125, 4:6, 4:129

post-translational control, 3:181 RTK pathway, 4:87-88 sequence of, 4:64 Insulin receptors, pleiotropic effects on, 3:154 Insulin resistance and diabetes, 1:210-211 insulin receptor gene defects, 1:211

Insulin-dependent diabetes mellitus (diabetes type 1), 1:209-210, 2:202

Insulin-like growth factor II (IGF2) Beckwith-Wiedemann syndrome and, 2:132 DNA methylation, 3:48 imprinting, 2:185 intelligence and, 2:211 Insurance discrimination, genetic testing and, 1:18, 1:68, 2:92-94, 2:100, 2:177, 3:4, 3:146, 3:192, 3:193 Integrase enzymes

HIV, 2:152-153, 2:155 of retroviruses, 4:35, 4:37 Inteins, post-translational control, 3:179

Intelligence, 2:207-211

Down syndrome, average IQ, 1:79

environmental factors, 2:207,

2:209-210, 2:211 eugenics concepts, 2:18 expanded concepts, 2:209 Flynn effect, 2:209 genes for, 2:5, 2:211 IQ measurements, 2:207-208 MENSA, 2:208 racial and ethnic differences,

2:209 standard tests, 2:208 twin and adoption studies,

2:207-208, 2:209-210 X chromosome role, 4:174 See also Mental retardation Intelligence quotient tests. See IQ tests

Interbreeding, 3:171, 3:173-174,

4:92-93 Intercalating agents, 3:88 Interchromatin compartment, 3:120,

3:121, 3:122-123, 3:122 Interchromatin granules (speckles),

3:120, 3:125 Intercrossing, defined, 1:147 Interference, crossover, 1:197, 3:12-13

Interferons as extranuclear hormones, 2:161 from genetically engineered bacteria, 1:63 Interleukin receptors, SCID and,

4:75, 4:76, 4:77 Interleukins as extranuclear hormones, 2:161 as gene therapy tools, 2:79 from genetically engineered bacteria, 1:63 Intermediate filaments, 3:120, 3:121 International Congress of Eugenics, 3:81

International Human Genome Consortium, 2:174, 2:176 International Rice Research Institute, 2:108 International World Conservation

Union (IUCN), 1:186 Internet, 2:211-213

bioinformatics tools, 1:53, 3:18 biotechnology resources, 1:64, 1:65

gene mutation listings, 2:143 genetic maps, 3:15 Genome Web site, 1:142, 2:176 Human Genome Project information, 2:174 International Human Genome

Consortium, 2:176 Mendelian Inheritance in Man, 3:23

Interphase, 2:112-113

banding techniques for, 1:129 defined, 1:134 DNA synthesis (S) phase, 1:104-105, 1:104, 3:25-26, 3:57-59 growth (G1 and G2) phases, 1:104-105, 3:57-59 Intersex organisms, 1:25, 3:77,

3:164, 4:80, 4:82, 4:127, 4:175 Interstitial region, 4:78 Intervention strategies, public health role, 3:218-219 Intestinal disorders. See Gastrointestinal disorders Intracytoplasmic sperm injection, 4:22

Intra-strand UV crosslinks, 1:244, 1:245

Intrauterine insemination, 4:24 Intravenous, defined, 2:145 Intrinsic terminators, 4:110 Introns, 1:12, 4:58

of antibody genes, 2:180, 2:182 defined, 1:224, 2:30, 3:56, 4:10 discovery of, 3:105-106

Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

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