Identification of the Biologically Relevant Assembly

Quaternary structure is defined as that level of form in which units of tertiary structure aggregate to form homo- or hetero-multimers. Consideration of the presence of a quaternary state is important in the understanding of a protein's biological function. For a PDB entry determined using X-ray crystallography, the deposited co-ordinates typically consist of the contents of the asymmetric unit (ASU). The deposited coordinates may, therefore, contain one or more complete macromolecule(s), some...

Contents

1 Annotation and Databases Status and Prospects 1 M. Hoebeke, H. Chiapello, J.-F. Gibrat, Ph. Bessieres and J. Garnier 1.2 Annotation of Genomic Data 3 1.3 Databases Concepts and Definitions 9 1.4 Access to Annotation Databases 12 Glossary 19 References 20 2 Survey of Sequence Databases Archival Projects 25 M. Magrane, M. Garcia-Pastor and R. Apweiler 2.2 Nucleotide Sequence Databases 27 2.6 UniProt 42 References 43 3 Survey of Sequence Databases Derived Databases 45 M. Pruess, N. Mulder and R....