Calcium homeostasis changes markedly [18,19]. Maternal total plasma calcium concentration falls, because albumin concentration falls, but unbound ionized calcium concentration is unchanged. Synthesis of 1,25 dihydrox-ycholecalciferol increases, promoting enhanced gastrointestinal calcium absorption. Parathyroid hormone (PTH) regulates the synthesis of 1,25 dihydroxyvitamin D in the proximal convoluted tubule. There is a fall in intact PTH during pregnancy but a doubling of 1,25 dihydroxyvitamin D; placentally synthesized PTH-related protein is also present in the maternal circulation.
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Once your pregnancy is over and done with, your baby is happily in your arms, and youre headed back home from the hospital, youll begin to realize that things have only just begun. Over the next few days, weeks, and months, youre going to increasingly notice that your entire life has changed in more ways than you could ever imagine.