The latter can be achieved using SSRIs . Increasing serotonin levels with SSRIs is clearly beneficial though none of these drugs now has pharmaceutical license for the management of PMS or PMDD. Fluoxetine 20 mg daily is usually sufficient to improve symptoms in most women. Side effects such as loss of libido may be partially avoided by administering the drug only during the luteal phase. Surprisingly the effect of the SSRIs is more instantaneous for PMS symptoms than is the case for depression. SSRIs are not licensed in the UK or Europe for PMS or PMDD. In the US Fluoxetine is licensed for PMDD under the name SARAFEM possibly to avoid the stigma of the name Prozac.
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The first trimester is very important for the mother and the baby. For most women it is common to find out about their pregnancy after they have missed their menstrual cycle. Since, not all women note their menstrual cycle and dates of intercourse, it may cause slight confusion about the exact date of conception. That is why most women find out that they are pregnant only after one month of pregnancy.