Preterm labour in multiple pregnancy, as with polyhy-dramnios, is attributed to uterine over-distension. Accordingly, there are no specific preventative measures aside from fetal reduction in high-order multiples, as discussed pp. 173-174.
Although hospitalization for bed rest has been practised in the past, there is little evidence to support its use. Indeed, meta-analysis of six randomized controlled trials suggests that bed rest in twins increases the chance of preterm delivery . With the exception of progesterone, prophylactic tocolytics are of no benefit in singletons, and thus it is not surprising that randomized trials similarly report no clear benefit in twins . There was no reduction in preterm birth or related outcomes in the only trial of 17-hydroxyprogesterone caproate in twins .
Was this article helpful?
Once your pregnancy is over and done with, your baby is happily in your arms, and youre headed back home from the hospital, youll begin to realize that things have only just begun. Over the next few days, weeks, and months, youre going to increasingly notice that your entire life has changed in more ways than you could ever imagine.