• POC is available in a wide range of delivery systems.
• The dose of progestogen determines the mode of action and side effects.
• Irregular vaginal bleeding is a common reason for discontinuation of low-dose POC which do not inhibit ovarian activity completely.
• Despite normal ovarian activity the LNG-IUS is associated with amenorrhoea because of endometrial atrophy.
• Depo-Provera® inhibits ovarian activity completely and most users have amenorrhoea.
• There are few data on long-term safety. Theoretically POC are safer than CHC.
• POC does not increase the risk of cardiovascular disease.
• Depo-Provera® is associated with decreased BMD.
• Depo-Provera® may be associated with an increased risk of some sexually transmitted infections.
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The first trimester is very important for the mother and the baby. For most women it is common to find out about their pregnancy after they have missed their menstrual cycle. Since, not all women note their menstrual cycle and dates of intercourse, it may cause slight confusion about the exact date of conception. That is why most women find out that they are pregnant only after one month of pregnancy.