Placental abruption may lead to the onset of preterm labour. This is thought to be through release of thrombin which stimulates myometrial contractions by protease activated receptors but independently of prostaglandin synthesis. This may explain the clinical impression that preterm labour associated with chorionamnionitis is often rapid whereas that associated with placental abruption is less so because in placental abruption there is no preripen-ing of the uterine cervix. Generation of thrombin may also play a role in preterm labour associated with chorionam-nionitis when it is released as a consequence of decidual haemorrhage.
Was this article helpful?
The first trimester is very important for the mother and the baby. For most women it is common to find out about their pregnancy after they have missed their menstrual cycle. Since, not all women note their menstrual cycle and dates of intercourse, it may cause slight confusion about the exact date of conception. That is why most women find out that they are pregnant only after one month of pregnancy.