Misoprostol is a highly effective agent for labour induction. Complications remain a matter of concern, particularly uterine hyperstimulation, precipitate labour, meconium-stained liquor, uterine rupture and postpartum haemorrhage. The available data suggest that risks can be minimized with the use of small dosages and that the starting dose should not exceed 25 ^g vaginally or orally. Limited evidence favours the oral over the vaginal route. There is a need for large-scale randomized trials comparing low-dose misoprostol regimens with conventional methods to determine with more certainty the relative rates of rare adverse outcomes.
Was this article helpful?
The first trimester is very important for the mother and the baby. For most women it is common to find out about their pregnancy after they have missed their menstrual cycle. Since, not all women note their menstrual cycle and dates of intercourse, it may cause slight confusion about the exact date of conception. That is why most women find out that they are pregnant only after one month of pregnancy.