The most important consideration with respect to labour induction is not how, but whether labour induction should be undertaken. Careful consideration must be given to potential benefits and risks to mother and baby, both physical and emotional, as well as to the state of the uterine cervix. When the cervix is unfavourable, oxytocin infusion and/or artificial rupture of the membranes are less likely to be effective in inducing labour. PGE2 administered vaginally in various formulations is the usual method of labour induction. Misoprostol is a less expensive method. At dosages around 25 ^g 4-hourly vaginally, both effectiveness and side effects appear similar to PGE2. Oral misoprostol may have advantages over the vaginal route of administration.
Mechanical methods of labour induction stimulate the cervix and lower uterine segment to release endogenous prostaglandins. Infusion of saline through an extra-amniotic Foley catheter appears to be an effective method of labour induction with low rate of uterine hyperstimulation.
Several other methods of labour induction have not been adequately assessed by randomized trials to be able to be advocated for general use.
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The first trimester is very important for the mother and the baby. For most women it is common to find out about their pregnancy after they have missed their menstrual cycle. Since, not all women note their menstrual cycle and dates of intercourse, it may cause slight confusion about the exact date of conception. That is why most women find out that they are pregnant only after one month of pregnancy.