The World Health Organization classification divides tro-phoblast disease into the premalignant partial and complete hydatidiform moles and the malignant disorders of invasive mole, choriocarcinoma and placental site tumours.
While there are some geographical and racial variations, with perhaps a higher incidence in Africa and Asia, the widely varying standards in the frequency and accuracy of pathology reporting makes comparisons difficult. However, the reported incidence of molar pregnancies in
Europe and North America is in the order of 0.2-1.5 per 1000 live births although these figures are also of limited accuracy .
Therelativerisk of hydatidiform moleis highest in pregnancies at the extremes of the reproductive age group with a modestly increased incidence in teenagers (1.3-fold) but a 10-fold increased relative risk in those aged 40 and over .
Historically the incidence of partial and complete molar pregnancies have been reported as approximately 3:1000 and 1:1000, respectively; however, this situation may well represent an over diagnosis of partial mole (PM). Nearly 40% of partial moles referred for expert review are reclassified as either complete moles (CMs) or non-molar pathologies .
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The first trimester is very important for the mother and the baby. For most women it is common to find out about their pregnancy after they have missed their menstrual cycle. Since, not all women note their menstrual cycle and dates of intercourse, it may cause slight confusion about the exact date of conception. That is why most women find out that they are pregnant only after one month of pregnancy.