Other cell mediators

Monitoring of eosinophils and their products may prove to be a useful outcome measure when assessing oral food challenges. IL-2 and gamma-interferon have also been reported as increasing after a positive challenge. These await further investigation before assessing their clinical significance.

The measurement of components of the complement cascade does not seem to be useful for the clinical evaluation of a patient with suspected food hypersensitivity, nor does the presence of immune complexes containing IgE or IgG in the serum of individuals following challenge seem to be useful in the diagnosis of food hypersensitivity.30

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