Xanthine Derivatives

Mechanism of action of drugs for asthma therapy. Schering Plough), which targeted airway receptors and exhibited reduced systemic side effects. A series of short-acting agents following the same general structure (shown in Figure 16.3A) were developed, including terbutaline (AstraZeneca) and fenoterol (Boehringer Ingelheim). As the chemistry of these drugs came to be understood, they were modified to achieve several things, including local metabolism to an active agent, increased...