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18-/2+

20+

- indicates negative result and + indicates positive result.

COC, cocaine; OPI, opiates; THC, tetrahydrocannabinol; AMP, amphetamines; MET, methamphetamines; PCP, phencyclidine; BZO, benzodiazepines.

- indicates negative result and + indicates positive result.

COC, cocaine; OPI, opiates; THC, tetrahydrocannabinol; AMP, amphetamines; MET, methamphetamines; PCP, phencyclidine; BZO, benzodiazepines.

results are summarized in Table 4. None of the subjects tested positive for PCP. Subjects who tested positive by Oratect for COC and OPI were likely to be tested positive by the urine drug screen. Oratect appeared to detect AMP better than urine test, and all subjects tested MET positive by Oratect were tested positive by Monitect. Confirmation of Oratect results by GC-MS ranged from 85 to 100% for COC, MET, AMP, and OPI.

All the volunteer subjects tested at the drug rehabilitation program appeared to have a job, and the tests were undertaken in the afternoon. It was suggested that this situation allowed little time for the test subject to smoke a marijuana cigarette immediately prior to being tested. Because the Oratect device tests for THC residue in the mouth cavity and the concentration of THC decreases rapidly after marijuana cigarette smoking (7), concentrations of THC might be too low to be detectable. The four samples that were detected positive by Oratect were all confirmed positive by GC-MS.

3.3. Correlation of Oratect Opiate Test With Oral-Fluid GC-MS and Urine Drug Screen

In another study (4), 10 normal human subjects were each administered one dose of Prometh with Codeine Cough Syrup (Alpharma USPD, Inc., Baltimore, MD) containing 10 mg of codeine phosphate, and their oral fluids and urine were analyzed for opiate after 1 h, 4 h, and 6 h. The urine samples were tested with Monitect PC11 Multiple Urine Drug Screen Test, while the oral-fluid samples were analyzed with three methods: Oratect screening test, Oratect confirmation test by GC-MS, and a laboratory-based test—Intercept oral-fluids

Table 3

Comparison of Enzyme-Linked Immunosorbent Assay (ELISA) and Oratect® Test Results

COC OPI PCP MET AMP

Table 3

Comparison of Enzyme-Linked Immunosorbent Assay (ELISA) and Oratect® Test Results

COC OPI PCP MET AMP

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