Info

10 ng/mL

Phencyclidine

8 d-3 wk

25 ng/mL

25 ng/mL

Benzodiazepines

3 or more d

300 ng/mL

300 ng/mL

Methadone

3 d

300 ng/mL

300 ng/mL

Methaqualone

2 wk

75 ng/mL

75 ng/mL

*The US Department of Health and Human Services has increased the cut-off for both screening and confirmation of opiates to 2000 ng/mL from 300 ng/mL in order to avoid false-positives caused by ingestion of food containing poppy seeds. GC-MS, gas chromatography-mass spectrometry.

*The US Department of Health and Human Services has increased the cut-off for both screening and confirmation of opiates to 2000 ng/mL from 300 ng/mL in order to avoid false-positives caused by ingestion of food containing poppy seeds. GC-MS, gas chromatography-mass spectrometry.

mandated to test under federal authority have instituted employee drug-testing programs in order to create a drug-free workplace. In fact, in 1986, President Reagan issued Executive Order No. 12564, directing all federal agencies to achieve a drug-free work environment. Guidelines for DOA testing were then developed by the Substance Abuse and Mental Health Services Administration (SAMHSA, formerly The National Institute on Drug Abuse [NIDA]) and became the gold standard for all drug-testing programs to follow. The overall testing process under mandatory testing consists of proper collection of specimen, initiation of chain of custody, and final analysis of specimen. Immunoas-says are available for quick screening of abused drugs in urine. This must be performed with US Food and Drug Administration (FDA)-approved methods. Positive screening results must then be confirmed by a SAMHSA-certified laboratory using gas chromatography(GC)-mass spectrometry (MS). The cut-off values for DOA testing are included in Table 1.

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