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Daniell, H., Streatfield, S.J. and Wycoff, K. (2001) Medical molecular farming production of antibodies, biopharmaceuticals and edible vaccines in plants. Trends Plant Sci., 6, 219-226. De Jung, T.J. (1995) Why fast-growing plants do not bother about defence. Oikos, 74, 545-548. De Luca, V. and Laflamme, P. (2001) The expanding universe of alkaloid biosynthesis. Curr. Opin. Plant Btol., 4, 225-233. De Luca, V. and St Pierre, B. (2000) The cell and developmental biology of alkaloid biosynthesis....

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Amount of red yeast rice sufficient to meet its sales projections. In February 1999, the FDA's ban on the import of red yeast rice was lifted, but it appealed the decision, and the saga is still going on (Israelsen, 1999). At the same time, Merck, which manufactures lovastatin, and Bristol-Myers Squibb, which produces pravastatin, a successful analogue, requested permission to sell to the general public their pharmaceutical-grade products at doses comparable to those found in the red yeast rice...

Introduction

Dietary supplements are in widespread use in the United States (Eisenberg et al., 1993, 1998 Kessler et al., 2001). This use continues to grow as more people, particularly the baby-boomers, become concerned about their access to health care, and the quality of that care, and seek complementary and alternative medical practices (Eisenberg et al., 1998 Foster et al., 2000 Kessler et al., 2001 Rainey and Cason, 2001). With the increasing advent of food that is heavily synthetic and influenced by...

General Test Chapter

Disintegration and dissolution of nutritional supplements Biological and chemical identification of articles of botanical origin Serenoa repens (Bartram) Small Family Arecaceae Final monograph Released 28 April 2000 Hypericum perforatum L. Family Hyperaceae Valeriana officinalis L. Family Valerianaceae Final monograph December 1997 Official in USP 24-NF19 In Process PF 26(6) Nov-Dec 2000 Draft under development Official in USP 24-NF19 In-Process Revision PF 26(2) Mar-Apr 2000 Official in USP...

Definitions of dietary supplements

The DSHEA defines dietary supplements for regulatory purpose within the United States. The Office of Dietary Supplements at the NIH needed to implement research priorities using this definition and yet in some manner group the wide array of supplement ingredients available in the marketplace into more manageable categories. A definition was needed that also could be interpreted more readily in terms of research projects. An operating definition was requested in meetings with the NIH Institute...

Dietary supplements of plant origin

In order to survive, plants have developed sophisticated mechanisms including an elaborate chemical arsenal of toxic substances, such as terpenes and alkaloids, that inhibit the growth of other plants and make them unattractive to predators da Rocha et al., 2001 see also chapter by Maffei . The ability of plants to produce bioactive compounds has been exploited by humans for thousands of years, and plant extracts and plant parts have been used since ancient times to cure various diseases. The...