Side Effects

The main side effects of metformin are nausea and occasionally diarrhea. You can limit these side effects by taking the medicine with food and starting at a low dose. The side effects are also dose dependent, and some people can tolerate only a low dose.

Rarely, people taking metformin can develop a serious medical condition called lactic acidosis, which can lead to death and so requires immediate hospitalization. The symptoms of lactic acidosis include nausea, vomiting, abdominal pain, rapid breathing, and feeling very unwell. People with liver failure, kidney failure, or severe heart failure are at a higher risk for lactic acidosis and therefore should not take this medicine.

Table 6-3 Oral Diabetes Medicines That Block the Activity of Enzymes That Break Down Starches

Generic Drug Name (Brand Name in Parentheses)

Strength

Daily Dose

Alpha-glucosidase inhibitors

Acarbose (Precose)

50 and 100 mg

75 to 300 mg in 3 divided doses before each meal; lasts 4 hours

Miglitol (Glyset)

25, 50, and 100 mg

75 to 300 mg in 3 divided doses before each meal; lasts 4 hours

Was this article helpful?

0 0

Post a comment