Clinical Application Questions

A 70-year-old man on multiple medications presents with dusky, asymmetric red plaque lesions first noted upon awakening. The patient complains of a deep burning itch and states he has had identical lesions at the same sites on three previous occasions over the past 2 years. You suspect a fixed drug eruption.

1. What history should be elicited from this patient pertaining to a fixed drug eruption?

2. What other variations in appearance of lesions may characterize fixed drug eruptions?

3. What treatment is appropriate for this patient's fixed drug eruption?

4. What is this patient's prognosis?

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