p-Hydroxybenzoic acid OH OH
Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Le Coz CJ (2004) Fiche d'éviction en cas d'hypersensibilité aux esters de l'acide para-hydroxybenzoïque (parahydroxybenzoates ou parabens). Ann Dermatol Venereol 131:309-310
PPD, p-Phenylenediamine, 4-Phenylenediamine CAS Registry Number [106-50-3] NH2
PPD is a colorless compound oxidized by hydrogen peroxide in the presence of ammonia. It is then polymerized to a color by a coupling agent. Although a well-known allergen in hair dyes, PPD can be found as a cause of contact dermatitis in chin rest stains or in milk testers. It is also a marker of group sensitivity to para amino compounds such as benzocaine, some azo-dyes and some previous antibacterial sulphonamides.
Bork K (1993) Allergic contact dermatitis on a violinist's neck from paraphenylenediamine in a chin rest stain. Contact Dermatitis 28:250-251 Frosch Pj, Burrows D, Camarasa JG, Dooms-Goossens A, Ducombs G, Lahti A, Menne T, Rycroft RJG, Shaw S, White IR, Wilkinson JD (1993) Allergic reactions to a hairdresser's series: results from 9 European centres. Contact Dermatitis 28: 180-183 Guerra L, Tosti A, Bardazzi F, Pigatto P, Lisi P, Santucci B, Valsecchi R, Schena D,Angelini G, Sertoli A,Ayala F, Kokelj F (1992) Contact dermatitis in hairdressers: the Italian experience. Gruppo Italiano Ricerca Dermatiti da Contatto e Ambientali. Contact Dermatitis 26: 101-107 Le Coz CJ, Lefebvre C, Keller F, Grosshans E (2000) Allergic contact dermatitis caused by skin painting (pseudotattooing) with black henna, a mixture of henna and p-phenylenediamine and its derivatives. Arch Dermatol 136 : 1515-1517 Rebandel P, Rudzki E (1995) Occupational allergy to p-phenylenediamine in milk testers. Contact Dermatitis 33 : 138
Was this article helpful?
The human body And Todays chemical infested world. Here is a news flash You are not allergic to pollen, pet dander, or whatever it is that makes your body revolt Rather, your body just can not handle that one thing, what ever it is, anymore, due to the massive barrage of toxic chemicals you and everyone else are ingesting every single day.