What Are The Pros And Cons Concerning Progesterone

Here are some key pros and cons regarding progesterone supplementation.


• Natural oral progesterone (Prometrium) is convenient because it is taken orally as a tablet.

• Suppositories target only your pelvic region, and thus you have fewer side effects throughout your body.

• Progesterone gel (Crinone) comes in an easy-to-use tamponlike applicator. The gel targets only your pelvic region, and thus you have fewer side effects.

• Progesterone in oil is highly effective at correcting hormonal imbalances and correcting menstrual and ovulation problems.


• Unlike natural progesterone, synthetic progesterone (Provera) is not safe to use once you become pregnant.

• Natural oral progesterone (Prometrium) may be associated with lower success rates than found with some other forms of progesterone.

• Natural oral progesterone (Prometrium) has side effects of dizziness or sleepiness.

• Progesterone suppositories are made by specialty pharmacies, which may be difficult to find in your area.

• Some women find the vaginal discharge associated with suppositories to be very unpleasant.

• The gel (Crinone) sticks so well in the vagina that some women experience vaginal irritation as a result of the buildup. Sometimes the accumulated gel must be removed every few days.

• Progesterone in oil must be injected, and a larger needle is required because of the thickness of the medication.

No one single form of progesterone is best for all women. Talk with your doctor about your particular situation and determine which method is best for you.

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