Index

Acanthopanax gracilistylus W. W. Sm., dopaminergic effects, 116, 117 Acanthopanax ricinifolius Seem., dopaminergic effects, 117, 119 Acanthopanax trifoliatus (L.) Merr., dopaminergic effects, 117 3-Acetylaltholactone, apoptosis induction, 199 1-O-Acetylbritannilatone, nitric oxide synthase inhibition, 40 Acriopsis javanica Reinw., GaBAergic effects, 101 Acronycine, topoisomerase inhibition, 175 Actinodaphnine, topoisomerase inhibition, 163 Alchornea rugoa (Lour.) Muell. Arg., topoisomerase inhibition, 182 Alchornea villosa (Benth.) Muell.-Arg., topoisomerase inhibition, 180, 181 Alizarin, serotonergic effects, 85 Alkengi, see Physalis alkengi Alligator yam, see Ipomoea digitata L. Altholactone, apoptosis induction, 200 Altingia excelsa Norhona, topoisomerase inhibition, 186, 187 y-Aminobutyric acid (GABA), inhibitory neurotransmission, 87 modulators,

Artemisia stelleriana Bess., 98, 99 Lamiaceae,

Leonotis nepetifolia R.Br, 95 Scutellaria baicalensis Georgi, 94, 95 Orchidaceae,

Acriopsis javanica Reinw., 101

Bulbophyllum vaginatum Reich. f., 101,102 Calanthe triplicata (Villem.)

Ames, 104 Calanthe vestita Lindl., 105 Dendrobium crumenatum Sw.,

105,106 Gastrodia elata Bl., 99, 100 Valerianaceae,

Nardostachys chinensis L., 90, 91 Nardostachys jatamansi DC., 91-93 Patrinia scabiosaefolia Link, 93, 94 Valeriana officinalis, 90 receptor types, 87 Amphetamine, structure, 127 Amsacrine, topoisomerase inhibition, 175 Annonaceae, see Artabotrys suaveolens Bl.; Cyathostemma micranthum (A.DC.) J. Sinclair.; Fissistigmafulgens (Hk. f. et Th.) Merr.; Fissistigma lanuginosum (Hook.f. & Thoms.) Merr.; Friesodielsia latifolia Hk. f. et Th.; Goniothalamus; Pseudouvaria setosa (King) J. Sinclair Annual lion's ear, see Leonotis nepetifolia R.Br

Anthraquinone, structure, 168 Apiaceae, see Bupleurum chinense DC Apigenin, GaBAergic effects, 96, 97 Apocynaceae, see Ervatamia corymbosa (Roxb.) King & Gamble; Ervatamia pandacaqui (Poir.) Pichon; Hunteria; Tabernanthe iboga; Trachelospermum asiaticum (Sieb. & Zucc.) Nak. Apomorphine, structure, 115

Apoptosis, inducers,

Annonaceae,

Goniothalamus, 195-201 Pseudouvaria setosa (King) J. Sinclair, 201, 202 Asteraceae,

Blumea riparia (Bl.) DC., 204-206 Elephantopus mollus Kunth.,

203-204 Lactuca indica L., 207, 208 Spilanthes paniculata Wall. ex DC, 206,207

manipulation in cancer management,

194,195 pathways, 194 Araliaceae, see Acanthopanax gracilistylus W. W. Sm.; Acanthopanax ricinifolius Seem.; Acanthopanax trifoliatus (L.) Merr.

Arctigenin, cyclooxygenase inhibition, 17 Ardisia villosa Roxb., lipoxygenase inhibition, 27 Ardisiaquinone G, lipoxygenase inhibition, 28

Arinica montana L., inflammation treatment, 1 Aristolochia indica L., phospholipase A2 inhibition, 6

Aristolochia kaempferi Willd., phospholipase

A2 inhibition, 6, 7 Aristolochia recurvilabra, phospholipase A2

inhibition, 7, 8 Aristolochiaceae, see Aristolochia indica L.; Aristolochia kaempferi Willd.; Aristolochia recurvilabra; Thottea grandiflora Rottb. Artabotrys suaveolens Bl., topoisomerase inhibition, 158, 159 Artemisia stelleriana Bess., GaBAergic effects, 98, 99 Aspirin, inflammation treatment, 2 Asteraceae, see Arinica montana L.; Artemisia stelleriana Bess.; Bidens bipinnata L.; Blumea riparia (Bl.) DC.; Carpesium divaricatum Sieb. et Zucc; Chrysanthemum sinense Sab.; Cirsium japonicum DC; Crossotephium chinense L.; Elephantopus mollus Kunth.; Inula chinensis Rupr. ex

Maxim; Lactuca indica L.; Matricaria chamolilla L.; Mikania cordata (Burm.f.) B.L. Robinson; Polygonum amphibium L.; Sigsbeckia glabrescens Mak.; Sigsbeckia orientalis L.; Spilanthes paniculata Wall. ex DC Atherospermidine, topoisomerase inhibition, 159

Atropine, structure, 59

Atroviridine, cyclooxygenase inhibition, 20

Baical scullcap, see Scutellaria baicalensis Georgi

Baicalein, GaBAergic effects, 96 Basil, see Ocimum basilicum L. Bengal madder, see Rubia cordifolia Benzodiazepines, mechanism of action, 89 Berberine, biological activity, 138 Betulin, topoisomerase inhibition, 184 Betulinic acid, anti-inflammatory activity, 49 Bicuculline, GaBAergic effects, 88, 89 Bidens bipinnata L., cyclooxygenase inhibition, 22

Blumea riparia (Bl.) DC., apoptosis induction, 204-206 Boldine, dopaminergic effects, 130 Bornyl caffeate, lipoxygenase inhibition, 31 Bromocriptine, structure, 115 Bufotenine, serotonergic effects, 62 Bulbophyllum vaginatum Reich. f., GaBAergic effects, 101, 102 Bupleurum chinense DC, lipoxygenase inhibition, 31, 32 Caffeine, mechanism of action, 125 structure, 124 Calanolide, cyclooxygenase inhibition, 19 Calanthe triplicata (Villem.) Ames,

GaBAergic effects, 104 Calanthe vestita Lindl., GaBAergic effects, 105

Camptothecin, structure, 156, 177 Cancer, see Chemotherapy

Cannabis sativa L., history of use, 57, 58 Caprofoliaceae, see Lonicera japonica

Thunb.; Sambucus javanica Reinw. ex Bl.; Weigela floribunda (Sieb. & Zucc.) K. Koch.

Cardiopetalolactone, apoptosis induction, 199 Carpesium divaricatum Sieb. et Zucc., nitric oxide synthase inhibition, 41, 42 Cassytha filiformis L., topoisomerase inhibition, 163 Cassythine, topoisomerase inhibition, 163 Catechin, serotonergic effects, 85, 86 Cathinine, dopaminergic effects, 127 Celastraceae, see Tripterygiumn wilfordii

Hook f. Celecoxib, structure, 15 Cepharantine, dopaminergic effects, 141 Chanoclavine, serotonergic effects, 68 Chelerythrine, topoisomerase inhibition, 178 Chemotherapy, cancer epidemiology, 155 drug discovery, 209, 210 overview of agents, 155-157 pharmacokinetics, 209 plant sources, see Apoptosis;

Topoisomerase Chinese honeysuckle, see Lonicera japonica Thunb.

Chinese lantern, see Physalis alkengi Chinese scullcap, see Scutellaria baicalensis Georgi

Chrismas orchard, see Calanthe triplicata

(Villem.) Ames Chrysanthemum sinense Sab., cyclooxygenase inhibition, 21 Cimicifuga foetida L., dopaminergic effects, 139,140

Cinnamon, anti-inflammatory activity, 49, 50 Cirsilineol, GaBAergic effects, 99

Cirsium japonicum DC, phospholipase A2

inhibition, 13 cisa-Ocimene, nitric oxide synthase inhibition, 44 Clusiaceae, see Garcinia atroviridis Griff.; Garcinia mangostana L.; Hypericum erectum Thunb.; Hypericum perforatum Convolvulaceae, see Ipomoea digitata L.; Ipomoea indica; Ipomoea obscura (L.) Ker-Gawl. Coptis teeta Wall., dopaminergic effects, 136-139

Coptisine, dopaminergic effects, 136, 137 Coronaridine, serotonergic effects, 74 Costunolide, nitric oxide synthase inhibition, 42

COX, see Cyclooxygenase

Crossotephium chinense L., phospholipase

A2 inhibition, 14 Cryptocarya griffithiana Wight, dopaminergic effects, 132, 133 Cryptolepine, topoisomerase inhibition, 209 Cryptotanshione, apoptosis induction, 193 Cumanin, nitric oxide synthase inhibition, 39 Curcuma, inflammation treatment, 3 Curcumin, properties, 3 Cyathostemma micranthum (A.DC.) J.

Sinclair., serotonergic effects, 65 Cyclooxygenase (COX), inhibitors, Asteraceae

Bidens bipinnata L., 22 Chrysanthemum sinense Sab., 21 Clusiaceae,

Garcinia atroviridis Griff., 20 Garcinia mangostana L., 18 cyclooxygenase-2 inhibitor safety, 15 Harpagophytum procumbens DC, 15 Laminiaceae,

Glechoma brevituba Kuprian, 26 Ocimum basilicum L., 24-26 Polygonum amphibium L., 23 Trachelospermum asiaticum (Sieb. & Zucc.) Nak., 16, 17 isoforms, 15

Damnacanthal, topoisomerase inhibition, 169

Damnacanthus indicus Gaertn., topoisomerase inhibition, 171, 172 Dehydrocostus lactone, nitric oxide synthase inhibition, 43 Dendrobine, GaBAergic effects, 106 Dendrobium crumenatum Sw., GaBAergic effects, 105, 106 Deoxygoniopypyrone A, apoptosis induction, 200

Deoxymikanolide, elastase inhibition, 37 Devil's claw, see Harpagophytum procumbens DC Devil's gut, see Cassytha filiformis L. Diaboline, glycinergic effects, 109 Diaryldimethylbutane lignans, topoisomerase inhibition, 172 Diazepam, structure, 96

Dicentrine, topoisomerase inhibition, 162 Digoniodiol, apoptosis induction, 200 Dihydrexidine, GaBAergic effects, 103

Diospyros sumatrana Miq., topoisomerase inhibition, 166 Diospyros toposiodes King & Gamble, topoisomerase inhibition, 166, 167 Discretamine, serotonergic effects, 64 Dodder-laurel, see Cassytha filiformis L. Dodonaea viscosa (L.) Jacq., dopaminergic effects, 126, 127 Dopa, structure, 115 Dopamine, modulators, Araliaceae,

Acanthopanax gracilistylus W. W.

Sm., 116, 117 Acanthopanax ricinifolius Seem.,

117,119 Acanthopanax trifoliatus (L.) Merr., 117 Lauraceae,

Cassytha filiformis L., 131, 132 Cryptocarya griffithiana Wight, 132, 133 Ranunculaceae,

Cimicifuga foetida L., 139, 140 Coptis teeta Wall., 136-139 Sapinaceae,

Dodonaea viscosa (L.) Jacq., 126,127

Erioglossum rubiginosum (Roxb.)

Bl., 125 Sapindus mukorossi Gaaertn., 125,126 Stephania cepharantha Hayata, 141,142

Tripterygiumn wilfordii Hook f., 129 Verbenaceae,

Vitex negundo L., 120, 121 Vitex quinata (Lour.) F.N.

Will., 123 Vitex trifolia L., 121, 123 Vitex vestita Wallich ex Schauer, 123,124 neurotransmission, 112-114 Parkinson's disease pathophysiology, 115 receptors, 112 structure, 113 therapeutic targeting, 115

Drosera rotundifolia L., elastase inhibition, 37, 38

Dwarf milkwort, see Polygala japonica Houtt.

Ebenaceae, see Diospyros sumatrana Miq.;

Diospyros toposiodes King & Gamble Echinacea, inflammation treatment, 2 Elastase, inflammatory response, 33 inhibitors, Asteraceae,

Mikania cordata (Burm.f.) B.L.

Robinson, 27, 34, 36 Sigsbeckia glabrescens Mak., 33, 34 Sigsbeckia orientalis L., 33 Drosera rotundifolia L., 37, 38 Elephantopus mollus Kunth., apoptosis induction, 203-204 Elymoclavine, serotonergic effects, 68 Embelin, apoptosis induction, 192, 194 Epigallocatechin gallate, apoptosis induction, 193,194

Erectquione A, lipoxygenase inhibition, 30 Ergine, serotonergic effects, 69

Erioglossum rubiginosum (Roxb.) Bl., dopaminergic effects, 125 Ervatamia corymbosa (Roxb.) King & Gamble, serotonergic effects, 74 Ervatamia pandacaqui (Poir.) Pichon, serotonergic effects, 73, 74 Estradiol, structure, 140 Etoposide, structure, 155 Euphorbiaceae, see Alchornea rugoa (Lour.) Muell. Arg.; Alchornea villosa (Benth.) Muell.-Arg.; Macaranga tribola (Reinw.) Muell.-Arg.; Phyllanthus acidus (L.) Skeels

Fissistigma fulgens (Hk. f. et Th.) Merr., topoisomerase inhibition, 159 Fissistigma lanuginosum(Hook.f. & Thoms.)

Merr., serotonergic effects, 63-65 Flavopiridol, apoptosis induction, 192 Florida hop bush, see Dodonaea viscosa (L.) Jacq.

Flumazenil, structure, 97

Fluoxetine, structure, 83 seco-3,4-Friedelin, topoisomerase inhibition, 182

Friesodielsia latifolia Hk. f. et Th., topoisomerase inhibition, 159, 160 GABA, see y_Aminobutyric acid Garcinia atroviridis Griff., cyclooxygenase inhibition, 20 Garcinia mangostana L., cyclooxygenase inhibition, 18 Gardnerilin A, apoptosis induction198 Gardnerilin B, apoptosis induction, 198 Gastrodia elata Bl., GaBAergic effects, 99,100

Genistein, antitumor activity, 210 Ginger, see Zingiber officinale L. Ginsenoside Rb1, dopaminergic effects, 117 Glaucine, dopaminergic effects, 130 Glechoma brevituba Kuprian, cyclooxygenase inhibition, 26 Glycine, modulators, Hunteria, 111 Loganiaceae,

Strychnos axillaris Colebr., 110 Strychnos ignatii Berg., 109 Strychnos minor Dennst., 110 neurotransmission, 107 receptors, 107 structure, 108 Glycyrrhiza glabra, inflammation treatment, 2 Goniodio, apoptosis induction, 199 Goniotetracin, apoptosis induction, 198 Goniothalamin, apoptosis induction, 199 dopaminergic effects, 134 Goniothalamus, apoptosis induction, 195-201

Gonotriol, apoptosis induction, 200 Gossypol, apoptosis induction, 193, 194 Ground burnut, see Tribulus terrestris L.

Hamamelidisceae, see Altingia excelsa Norhona

Harmaline, serotonergic effects, 62, 63 Harmine, serotonergic effects, 62, 63 Harmol, serotonergic effects, 76

Harpagophytum procumbens DC, cyclooxygenase inhibition, 15 Hemp, see Cannabis sativa L. Hernandiaceae, see Illigera luzonensis L. Hernone, topoisomerase inhibition, 164 Hirsutine, serotonergic effects, 87 Hispidulin, GaBAergic effects, 99 Horminone, topoisomerase inhibition, 188 Horsfieldia amygdalinia (Wall.) Warb, phos-

pholipase A2 inhibition, 8, 9 Horsfieldia glabra (Bl.) Warb., serotonergic effects, 67, 68 Horsfieldia valida (Miq.) Warb., phospholi-

pase A2 inhibition, 9, 10 Hunteria, glycinergic effects, 111 Hydrastine, dopaminergic effects, 134

4-Hydroxybenzaldehyde, GaBAergic effects, 100

19' (S) Hydroxyconoduramine, serotonergic effects, 75

5-Hydroxyl-N,N-dimethyl tryptamine, sero-tonergic effects, 66

5-Hydroxy-indoline, dopaminergic effects, 132 4-Hydroxy-3-methoxybenzaldehyde,

GaBAergic effects, 100 16-Hydroxyyatein, topoisomerase inhibition, 164 Hyperforin, lipoxygenase inhibition, 29 Hypericin, cyclooxygenase inhibition, 19 Hypericum erectum Thunb., lipoxygenase inhibition, 29, 30 Hypericum perforatum, lipoxygenase inhibition, 28

Ibericin, topoisomerase inhibition, 170 Ibogaine, serotonergic effects, 72 Icajine, glycinergic effects, 108 Iiriodenine, structure, 157 Illigera luzonensis L., topoisomerase inhibition, 164,165 Indian Aristolochia, see Aristolochia indica L. Indian madder, see Rubia cordifolia Ineupatorolide A, apoptosis induction, 203 Inflammation, see Cyclooxygenase; Elastase; Lipoxygenase; Nitric oxide synthase; Phospholipase A2 Inula chinensis Rupr. ex Maxim., nitric oxide synthase inhibition, 39, 40

Ipomoea digitata L., serotonergic effects, 70 Ipomoea indica, serotonergic effects, 70, 72 Ipomoea obscura (L.) Ker-Gawl., serotonergic effects, 69 Irinotecan, structure, 156 Isodiospyrin, topoisomerase inhibition, 165 Japanese peppercorn, see Zanthoxylum piperitum (L.) DC. Japanese prickly ash, see Zanthoxylum ailanthoides Sieb. & Zucc. Japanese thistle, see Cirsium japonicum DC Kalopanaxsaponin A, dopaminergic effects, 119 Kanna, history of use, 61 Kavain, dopaminergic effects, 134 Knoxia valerianoide Thorel, topoisomerase inhibition, 170, 171 Knoxiadin, topoisomerase inhibition, 170 Korean pepper, see Zanthoxylum schinifolium Zieb. & Zucc., 179

Labdane F2, cyclooxygenase inhibition, 24 Lactuca indica L., apoptosis induction, 207,208

Lamiaceae, see Artemisia stelleriana Bess.; Glechoma brevituba Kuprian; Leonotis nepetifolia R.Br; Ocimum basilicum L.; Scutellaria baicalensis Georgi Cassytha filiformis L., dopaminergic effects, 131,132

Lauraceae, see Cassytha filiformis L.; Cryptocarya griffithiana Wight; Lindera tzumu Hemsl.; Litsea cuceba (Lour.) Pers.; Litsea odorifera Val.; Neolitsea zeylanica Nees (Merr.); Persea thunbergii (Sieb. & Zucc.) Kosterm

Laurotetanine, nitric oxide synthase inhibition, 45 Leonotis nepetifolia R.Br, GaBAergic effects, 95 Lindera tzumu Hemsl., topoisomerase inhibition, 162 Linderalactone, nitric oxide synthase inhibition, 43 Lipoxygenase, inflammation role, 27 inhibitors,

Ardisia villosa Roxb., 27 Asteraceae, 30

Bupleurum chinense DC, 31, 32 Clusiaceae,

Hypericum erectum Thunb., 29, 30 Hypericum perforatum, 28 Liquorice, see Glycyrrhiza glabra Liriodenine, serotonergic effects, 65 Litsea cuceba (Lour.) Pers., nitric oxide synthase inhibition, 44, 45 Litsea odorifera Val., nitric oxide synthase inhibition, 45 Loganiaceae, see Strychnos axillaris Colebr.; Strychnos ignatii Berg.; Strychnos minor Dennst. Lonicera japonica Thunb., phospholipase A2

inhibition, 10, 11 LSD, see Lysergic acid diethylamide Lupeol, anti-inflammatory activity, 49 topoisomerase inhibition, 184 Luteolin, apoptosis induction, 208 Lysergic acid diethylamide (LSD), serotonergic effects, 69, 76

Macaranga tribola (Reinw.) Muell.-Arg., topoisomerase inhibition, 184-186 Macrolactam indole alkaloid, serotonergic effects, 69 Makino, see Crossotephium chinense L. Malay gooseberry, see Phyllanthus acidus

(L.) Skeels Mamiaceae, see Salvia japonica Thunb.; Salvia miltiorrhiza Bunge; Salvia plebeia R.Br. Mandragora officinarum L., history of use, 57 y-Mangostin, cyclooxygenase inhibition, 18 Matricaria chamolilla L., inflammation treatment, 1 Menispermacaeae, see Stephania cepharantha Hayata Mesembrine, serotonergic effects, 61 structure, 60 N-Methyl-actinodaphnine, topoisomerase inhibition, 165 Mikania cordata (Burm.f.) B.L. Robinson, elastase inhibition, 34, 36, 27

Mikanolide, elastase inhibition, 37 Mitoxantrone, structure, 168 Mitragynine, structure, 143 Molephantinin, apoptosis induction, 203

Morinda officinalis How, topoisomerase inhibition, 173, 174 Morphine, structure, 59, 143 Myristica fragrans, history of use, 57, 58

Myristicaceae, see Horsfieldia amygdalinia (Wall.) Warb; Horsfieldia glabra (Bl.) Warb.; Horsfieldia valida (Miq.) Warb., 9, 10 Myristicin, central nervous system effects, 58 structure, 59 Myrsinaceae, see Ardisia villosa Roxb.

Nardosinone, GaBAergic effects, 92 Nardostachys chinensis L., GaBAergic effects, 90, 91 Nardostachys jatamansi DC., GaBAergic effects, 91-93 Neocimicidine, dopaminergic effects, 140 Neolitsea zeylanica Nees (Merr.), nitric oxide synthase inhibition, 42, 4 Neonauclea pallida (Reinw. ex Havil.) Bakh f., topoisomerase inhibition, 172, 173 Nipecotic acid, glycinergic effects, 108 Nitidine, topoisomerase inhibition, 177 Nitric oxide synthase (NOS), functions, 38

inflammatory response, 39 inhibitors, Asteraceae,

Carpesium divaricatum Sieb. et

Zucc., 41, 42 Inula chinensis Rupr. ex Maxim., 39, 40 Lauraceae,

Litsea cuceba (Lour.) Pers., 44, 45 Litsea odorifera Val., 45 Neolitsea zeylanica Nees (Merr.), 42, 43 Physalis alkengi, 46, 47 Nordamnacanthal, topoisomerase inhibition, 169 Norharman, serotonergic effects, 80 Nornuciferine, serotonergic effects, 63

NOS, see Nitric oxide synthase Nutmeg, see Myristica fragrans Nymphone, topoisomerase inhibition, 164

Obscure morning glory, see Ipomoea obscua

(L.) Ker-Gawl. Ocean blue morning glory, see Ipomoea indica

Ochnaflavone, phospholipase A2 inhibition, 11 Ocimum basilicum L., cyclooxygenase inhibition, 24-26 Oleanene aglycone, dopaminergic effects, 117

Opium, see Papaver somniferum Orchidaceae, see Acriopsis javanica Reinw.; Bulbophyllum vaginatum Reich. f.; Calanthe triplicata (Villem.) Ames; Calanthe vestita Lindl.; Dendrobium crumenatum Sw.; Gastrodia elata Bl. Oroxylin A, GaBAergic effects, 94, 96 Palmatine, dopaminergic effects, 138 Papaver somniferum, history of use, 57, 58 Para cress, see Spilanthes paniculata Wall. ex DC

Patrinia scabiosaefolia Link, GaBAergic effects, 93, 94 Peganum harmala L., serotonergic effects, 76 Perlolyrine, serotonergic effects, 77 Persea thunbergii (Sieb. & Zucc.) Kosterm., topoisomerase inhibition, 161 Peyote, history of use, 57 Phospholipase A2, inflammation mediation, 4, 5 inhibitors,

Aristolochiaceae,

Aristolochia indica L., 6 Aristolochia kaempferi Willd., 6, 7 Aristolochia recurvilabra, 7, 8 Thottea grandiflora Rottb., 8 Asteraceae,

Cirsium japonicum DC, 13 Crossotephium chinense L., 14 Caprofoliaceae,

Lonicera japonica Thunb., 10, 11 Sambucus javanica Reinw. ex Bl., 11 Weigela floribunda (Sieb. & Zucc.)

Myristicaceae,

Horsfieldia amygdalinia (Wall.)

Phyllanthus acidus (L.) Skeels, topoisomerase inhibition, 182-184 Physalin F, nitric oxide synthase inhibition, 46 Physalis alkengi, nitric oxide synthase inhibition, 46, 47 Picrotoxinin, GaBAergic effects, 87, 88 Pigeon orchid, see Dendrobium crumenatum Sw. Polanisia dodecandra, antitumor activity, 209,210

Polyacetylene, lipoxygenase inhibition, 30

Polygala glomerata Lour., serotonergic effects, 80, 81 Polygala japonica Houtt., serotonergic effects, 79

Polygala tenuifolia, serotonergic effects, 78, 79

Polygalaceae, see Polygala glomerata Lour.; Polygala japonica Houtt.; Polygala tenuifolia

Polygalasaponin aglycone, serotonergic effects, 78

Polygonum amphibium L., cyclooxygenase inhibition, 23 Procatechuic acid, apoptosis induction, 205 Prosmatomeris albiflora Thaw, non King, topoisomerase inhibition, 168-170 Pseudoneilinderane, nitric oxide synthase inhibition, 43 Pseudouvaria setosa (King) J. Sinclair, apoptosis induction, 201, 202 Psychotria adenophylla Wall., serotonergic effects, 82, 83 Puncture vine, see Tribulus terrestris L. Purpurin, serotonergic effects, 85

Qurcetin, elastase inhibition, 38 Ranunculaceae, see Cimicifuga foetida L.;

Coptis teeta Wall. Reticuline, dopaminergic effects, 130 Rofecoxib, structure, 26 Rotundifuran, dopaminergic effects, 122

Round leaf sundew, see Drosera rotundifolia L. Rubia cordifolia, serotonergic effects, 83-85 Rubiaceae, see Damnacanthus indicus

Gaertn.; Knoxia valerianoide Thorel; Morinda officinalis How; Neonauclea pallida (Reinw. ex Havil.) Bakh f.; Prosmatomeris albiflora Thaw, non King; Psychotria adenophylla Wall.; Rubia cordifolia; Uncaria rhynchophylla Miq. Rubiadin, topoisomerase inhibition, 169 Rubiadin-1-methyl ester, topoisomerase inhibition, 169 Rutaceae, see Zanthoxylum ailanthoides Sieb. & Zucc.; Zanthoxylum bungei Planch.; Zanthoxylum piperitum (L.) DC.; Zanthoxylum schinifolium Zieb. & Zucc.

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