This benzylisoquinoline alkaloid inhibits in vitro the specific bonding of [3H] dopamine to dopamine receptors and abrogates amphetamine-induced circling behavior in rodents with unilateral degeneration of dopaminergic neurons in the corpus striatum (109).
Cassytha filiformis L. (Cassytha guinensis Schum.), or dodder-laurel, snotty-gobble, devil's gut, or chemar batu (Malay)., is a slender epiphytic climber common on the seashores of Africa and the Asia-Pacific region. At first glance, the plant looks like a bunch of threads, but a closer observation reveals fleshy stems, tiny yellowish flowers, and whitish berries. In Malaysia, the plant is used to promote the growth of hair. Indonesians use the plant internally as vermifuge and laxative. In the Philippines, a decoction of the fresh plant is drunk to precipitate childbirth and to remove blood from saliva. In Taiwan, the stems are used as a diuretic and emmenagogue. In Vietnam, the plant is used to treat syphilis and lung diseases. The plant is known to elaborate series of aporphine alkaloids, including ocoteine, an aj-adrenoreceptor antagonist.
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